| 1 | 15:30 |  | Pogon Siedlce - Termalica B-B. | 2/+bts | 30.00 | 4.30 | 1 : 2 |
| 1 | 18:30 | | Cobresal - Union La Calera | 1 | 30.00 | 2.08 | 4 : 0 |
| 2 | 14:00 |  | Brommapojkarna - Malmo FF | 2/+bts | 30.00 | 3.55 | 1 : 2 |
| 3 | 19:05 | | Orebro - Varnamo | 1 | 30.00 | 2.17 | 1 : 3 |
| 3 | 20:30 | | FCSB - Farul Constanta | 1/+bts | 30.00 | 3.30 | 2 : 2 |
| 4 | 21:00 | | Shamrock Rovers (Irl) - Egnatia (Alb) | 1 | 30.00 | 1.96 | 3 : 1 |
| 4 | 18:45 | | Kiryat Shmona - Sakhnin | 1/+bts | 30.00 | 3.90 | 1 : 0 |
| 5 | 21:15 |  | Hafnarfjordur - KR Reykjavik | x | 30.00 | 4.34 | 1 : 1 |
| 5 | 16:30 | | Podhale Nowy Targ - Chojniczanka | 1/+bts | 30.00 | 3.80 | 2 : 0 |
| 6 | 19:00 | | Lincoln Red Imps (Gib) - Omonia (Cyp) | x | 30.00 | 4.13 | 1 : 1 |
| 6 | 19:45 | | PAOK - Anderlecht | 1/+bts | 30.00 | 3.50 | 0 : 1 |
| 7 | 12:25 | | Yokohama F. Marinos - Kashima Antlers | 1/+bts | 30.00 | 6.70 | 3 : 4 |
| 7 | 12:30 | | West Torrens - West Adelaide | x | 30.00 | 4.18 | 6 : 1 |
| 8 | 10:30 | | Pogon Szczecin W - Leczna W | 2/+bts | 30.00 | 3.85 | 1 : 3 |
| 8 | 17:30 | | Pogon Szczecin - Motor Lublin | 1 | 30.00 | 2.04 | 3 : 1 |
| 9 | 14:45 | | Slask Wroclaw - Cracovia | x | 30.00 | 3.30 | 0 : 0 |
| 9 | 13:30 | | St. Pauli - Greuther Furth | 1/+bts | 30.00 | 3.15 | 1 : 1 |
| 10 | 19:00 | | Benfica B - Leixoes | 1/+bts | 30.00 | 3.85 | 1 : 0 |
| 10 | 19:00 | | Skierniewice - Arka Gdynia | x | 30.00 | 3.55 | 2 : 0 |
| 11 | 12:30 | | Gangwon - Gamba Osaka | 2/+bts | 30.00 | 4.90 | 0 : 0 |
| 11 | 19:30 | | Nijmegen (Ned) - Olympiacos Piraeus (Gre) | 1 | 30.00 | 2.73 | 1 : 1 |
| 12 | 18:00 | | GKS Katowice - Hapoel Tel Aviv | 2/+bts | 30.00 | 6.20 | 2 : 1 |
| 12 | 21:00 | | PSG - Aston Villa | x | 30.00 | 3.85 | 2 : 1 |
| 18 | 21:00 | | Fenerbahce (Tur) - Lyon (Fra) | x | 30.00 | 3.57 | 1 : 1 |
| 18 | 13:35 | | Shanghai Shenhua - Beijing Guoan | 2/+bts | 30.00 | 4.00 | 0 : 3 |
| 19 | 18:00 | | Kluczevia Stargard - Gedania Gdańsk | 2 | 30.00 | 4.89 | 2 : 2 |
| 19 | 21:00 | | Slovan Bratislava - Celje | 1/+bts | 30.00 | 3.60 | 1 : 1 |
| 20 | 20:15 | | Sion - Ajax /Conference League | 2/+3,5 | 30.00 | 3.90 | 2 : 4 |
| 20 | 20:45 | | Concarneau - Villefranche | x | 30.00 | 3.27 | 2 : 0 |
| 21 | 20:00 | | Vitesse - Almere City | 2/+bts | 30.00 | 4.40 | 0 : 3 |
| 21 | 21:00 | | Betis - Real Sociedad | x | 30.00 | 3.35 | 1 : 0 |
| 22 | 20:15 | | Slask Wroclaw - Widzew Lodz | 1/+bts | 30.00 | 4.70 | Calcio |